People

Afari N


Publications

  • Clemens JQ, Locke K Jr, Landis JR, Kreder K, Rodriguez LV, Yang CC, Tu FF, Harte SE, Schrepf A, Farrar JT, Sutcliffe S, Naliboff BD, Williams DA, Afari N, Spitznagle T, Taple BJ, Lai HH; Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. Validation of a simple body map to measure widespread pain in urologic chronic pelvic pain syndrome: A MAPP research network study. Neurourol Urodyn. 2024 Mar;43(3):727-737. doi: 10.1002/nau.25400. Epub 2024 Jan 25. [PMID: 38270336] [PMC10981467]
    Keywords: chronic prostatitis with chronic pelvic pain syndrome;  interstitial cystitis/bladder pain syndrome; pelvic pain; prostate; urinary bladder.

  • Pierce J, Harte SE, Afari N, Bradley CS, Griffith JW, Kim J, Lutgendorf S, Naliboff BD, Rodriguez LV, Taple BJ, Williams D, Harris RE, Schrepf A; MAPP Research Network. Mediators of the association between childhood trauma and pain sensitivity in adulthood: a Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network analysis. Pain. 2023 Sep 1;164(9):1995-2008. doi: 10.1097/j.pain.0000000000002895. Epub 2023 May 5. [PMID: 37144687] [PMC10440258]
    Keywords: Trauma, Childhood abuse, Pain sensitivity, Quantitative sensory testing.
  • Stephens-Shields AJ, Lai HH, Landis JR, Kreder K, Rodriguez LV, Naliboff BD, Afari N, Sutcliffe S, Moldwin R, Griffith JW, Clemens JQ, Bradley CS, Quallich S, Gupta P, Harte SE, Farrar JT. Clinically Important Differences for Pain and Urinary Symptoms in Urological Chronic Pelvic Pain Syndrome: A MAPP Network Study. J Urol. 2023 Jun;209(6):1132-1140. doi: 10.1097/JU.0000000000003394. Epub 2023 Feb 27. [PMID: 36848118] [PMC11062515]
    Keywords: cystitis, interstitial; minimal clinically important difference; pelvic pain; research design; treatment outcome.
  • Schrepf A, Gallop R, Naliboff B, Harte SE, Afari N, Lai HH, Pontari M, McKernan LC, Strachan E, Kreder KJ, As-Sanie SA, Rodriguez LV, Griffith JW, Williams DA; Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. Clinical Phenotyping for Pain Mechanisms in Urologic Chronic Pelvic Pain Syndromes: A Mapp Research Network Study. J Pain. 2022 Sep;23(9):1594-1603. doi: 10.1016/j.jpain.2022.03.240. Epub 2022 Apr 25. [PMID: 35472518] [PMC10547025]
    Keywords: Nociceptive pain; central nervous system sensitization; chronic pain; cystitis; neuropathic pain.

  • Gasperi M, Afari N, Goldberg J, Suri P, Panizzon MS. Pain and Trauma: The Role of Criterion A Trauma and Stressful Life Events in the Pain and PTSD Relationship. J Pain. 2021 Nov;22(11):1506-1517. doi: 10.1016/j.jpain.2021.04.015. Epub 2021 May 21. [PMID: 34029685] [PMC8578317]
    Keywords: Pain intensity, Post-traumatic stress disorder, Trauma, Stressful life events, Veterans; DK082325 (BUCHWALD, D)

  • Gasperi M, Panizzon M, Goldberg J, Buchwald D, Afari N. Posttraumatic Stress Disorder and Chronic Pain Conditions in Men: A Twin Study. Psychosom Med. 2021 Feb-Mar 01;83(2):109-117. doi: 10.1097/PSY.0000000000000899. [PMID: 33337593] [PMC7858228]
    Keywords: posttraumatic stress disorder, chronic pain, comorbidity, twins, genetics; DK082325 (BUCHWALD, D)

  • Clemens JQ, Stephens-Shields AJ, Newcomb C, Rodriguez LV, Lai HH, Bradley CS, Naliboff BD, Griffith JW, Taple BJ, Gupta P, Afari N, Harte SE, Strachan E, Guo W, Landis JR. Correlates of 1-year change in quality of life in patients with urologic chronic pelvic pain syndrome: findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. J Urol. 2020 Oct;204(4):754-759. doi: 10.1097/JU.0000000000001080. Epub 2020 Apr 15. [PMID: 32294397] [PMC7483873]
    Keywords: cystitis; interstitial; prostatitis.
  • Afari N, Buchwald D, Clauw D, Hong B, Hou X, Krieger JN, Mullins C, Stephens-Shields AJ, Gasperi M, Williams DA; MAPP Research Network. A MAPP network case-control study of urological chronic pelvic pain compared with nonurological pain conditions. Clin J Pain. 2020 Jan;36(1):8-15. doi: 10.1097/AJP.0000000000000769. Epub 2019 Sep 26. [PMID: 31794439] [PMC7055954]
    Keywords: catastrophizing, chronic fatigue syndrome, fibromyalgia, irritable bowel syndrome, pelvic pain.
  • Gasperi M, Krieger JN, Panizzon MS, Goldberg J, Buchwald D, Afari N. Genetic and environmental influences on urinary conditions in men: a classical twin study. Urology. 2019 Jul;129:54-59. doi: 10.1016/j.urology.2019.04.005. Epub 2019 Apr 13. [PMID: 30986484] [PMC6592774]
    Keywords: benign prostatic hypoplasia, chronic prostatitis, comorbidity, lower urinary tract symptoms, prostate cancer, twins.
  • Harte SE, Schrepf A, Gallop R, Kruger GH, Lai HHH, Sutcliffe S, Halvorson M, Ichesco E, Naliboff BD, Afari N, Harris RE, Farrar JT, Tu F, Landis JR, Clauw DJ; MAPP Research Network. Quantitative assessment of nonpelvic pressure pain sensitivity in urologic chronic pelvic pain syndrome: a MAPP Research Network study. Pain. 2019 Jun;160(6):1270-1280. doi: 10.1097/j.pain.0000000000001505. [PMID: 31050659] [PMC6527452]
    Keywords: Quantitative sensory testing; Pressure pain threshold; Interstitial cystitis; Bladder pain syndrome; Chronic prostatitis; Chronic pelvic pain syndrome; Central sensitization.
  • Schrepf A, Williams DA, Gallop R, Naliboff BD, Basu N, Kaplan C, Harper DE, Landis JR, Clemens JQ, Strachan E, Griffith JW, Afari N, Hassett A, Pontari MA, Clauw DJ, Harte SE; MAPP Research Network. Sensory sensitivity and symptom severity represent unique dimensions of chronic pain: a MAPP Research Network study. Pain. 2018 Oct;159(10):2002-2011. doi: 10.1097/j.pain.0000000000001299. [PMID: 29863527] [PMC6705610]
    Keywords: Interstitial cystitis/painful bladder syndrome; Factor analysis; statistical; Fibromyalgia; Central nervous system sensitization; Interoception.
  • Gasperi M, Krieger JN, Forsberg C, Goldberg J, Buchwald D, Afari N. Chronic prostatitis and comorbid non-urological overlapping pain conditions: A co-twin control study. J Psychosom Res. 2017 Nov;102:29-33. doi: 10.1016/j.jpsychores.2017.09.005. Epub 2017 Sep 6. [PMID: 28992894] [PMC5683425]
    Keywords: Chronic fatigue syndrome; Chronic pelvic pain syndrome; Chronic prostatitis; Comorbidity; Discordant twins; Fibromyalgia; Irritable bowel syndrome; Lower urinary tract symptoms; Migraine headaches; Temporomandibular joint disorder; Twin research.
  • Afari N, Gasperi M, Forsberg CW, Goldberg J, Buchwald D, Krieger JN. Heritability of lower urinary tract symptoms in men: a twin study. J Urol. 2016 Nov;196(5):1486-1492. doi: 10.1016/j.juro.2016.06.018. Epub 2016 Jun 14. [PMID: 27312318] [PMC5069121]
    Keywords: lower urinary tract symptoms; heritable quantitative trait; twins.
  • Griffith JW, Stephens-Shields AJ, Hou X, Naliboff BD, Pontari M, Edwards TC, Williams DA, Clemens JQ, Afari N, Tu F, Lloyd RB, Patrick DL, Mullins C, Kusek JW, Sutcliffe S, Hong BA, Lai HH, Krieger JN, Bradley CS, Kim J, Landis JR. Pain and urinary symptoms should not be combined into a single score: psychometric findings from the MAPP Research Network. J Urol. 2016 Apr;195(4 Pt 1):949-54. doi: 10.1016/j.juro.2015.11.012. Epub 2015 Nov 14. [PMID: 26585679] [PMC4867140]
    Keywords: chronic pain; cystitis, interstitial; factor analysis, statistical; prostatitis; urinary bladder.
  • Godfrey KM, Strachan E, Mostoufi S, Poeschla B, Succop A, Afari N. Familial contributions to self-reported sleep and pain in female twins. Pain Med. 2016 Jan;17(1):33-9. doi: 10.1111/pme.12894. [PMID: 26271474] [PMC4753149]
    Keywords: Pain, Sleep, Females, Twins, Genetics, Familial Factors.
  • Naliboff BD, Stephens AJ, Afari N, Lai H, Krieger JN, Hong B, Lutgendorf S, Strachan E, Williams D; MAPP Research Network. Widespread psychosocial difficulties in men and women with urologic chronic pelvic pain syndromes: case-control findings from the multidisciplinary approach to the study of chronic pelvic pain research network. Urology. 2015 Jun;85(6):1319-27. doi: 10.1016/j.urology.2015.02.047. [PMID: 26099876] [PMC4479402]
    Keywords: chronic pain; pelvic pain; severity of illness index; urologic diseases.
  • Krieger JN, Stephens AJ, Landis JR, Clemens JQ, Kreder K, Lai HH, Afari N, Rodríguez L, Schaeffer A, Mackey S, Andriole GL, Williams DA; MAPP Research Network. Relationship between chronic nonurological associated somatic syndromes and symptom severity in urological chronic pelvic pain syndromes: baseline evaluation of the MAPP study. J Urol. 2015 Apr;193(4):1254-62. doi: 10.1016/j.juro.2014.10.086. Epub 2014 Oct 22. [PMID: 25444992] [PMC4497586]
    Keywords: cystitis; female; interstitial; male; questionnaires; urinary bladder.
  • Landis JR, Williams DA, Lucia MS, Clauw DJ, Naliboff BD, Robinson NA, van Bokhoven A, Sutcliffe S, Schaeffer AJ, Rodriguez LV, Mayer EA, Lai HH, Krieger JN, Kreder KJ, Afari N, Andriole GL, Bradley CS, Griffith JW, Klumpp DJ, Hong BA, Lutgendorf SK, Buchwald D, Yang CC, Mackey S, Pontari MA, Hanno P, Kusek JW, Mullins C, Clemens JQ; MAPP Research Network Study Group. The MAPP research network: design, patient characterization and operations. BMC Urol. 2014 Aug 1;14:58. doi: 10.1186/1471-2490-14-58. [PMID: 25085119] [PMC4126395]
    Keywords: Urologic chronic pelvic pain syndromes; Interstitial cystitis; Chronic prostatitis; Urine biomarkers; Plasma biomarkers; Non-urologic associated syndromes; Quantitative sensory testing (QST); Neuroimaging.
  • Bullones Rodríguez MÁ, Afari N, Buchwald DS; National Institute of Diabetes and Digestive and Kidney Diseases Working Group on Urological Chronic Pelvic Pain. Evidence for overlap between urological and nonurological unexplained clinical conditions. J Urol. 2013 Jan;189(1 Suppl):S66-74. doi: 10.1016/j.juro.2012.11.019. [PMID: 23234637] [PMC9159381]
    Keywords: urogenital system; fatigue syndrome; chronic; fibromyalgia; irritable bowel syndrome; temporomandibular joint disorders.
  • Rodríguez MÁ, Afari N, Buchwald DS. Evidence for overlap between urological and nonurological unexplained clinical conditions. J Urol. 2009 Nov;182(5):2123-31. doi: 10.1016/j.juro.2009.07.036. Epub 2009 Sep 16. [PMID: 19758633] [PMC2957306]
    Keywords: urogenital system; fatigue syndrome; chronic; fibromyalgia; irritable bowel syndrome; temporomandibular joint disorders.