People

Klumpp DJ


Publications

  • Mawla I, Schrepf A, Ichesco E, Harte SE, Klumpp DJ, Griffith JW, Strachan E, Yang CC, Lai H, Andriole G, Magnotta VA, Kreder K, Clauw DJ, Harris RE, Clemens JQ, Landis JR, Mullins C, Rodriguez LV, Mayer EA, Kutch JJ. Natural bladder filling alters resting brain function at multiple spatial scales: a proof-of-concept MAPP Network Neuroimaging Study. Sci Rep. 2020 Nov 16;10(1):19901. doi: 10.1038/s41598-020-76857-x. [PMID: 33199816] [PMC7669903]
    Keywords: bladder; functional magnetic resonance imaging.
  • Yang W, Yaggie RE, Schaeffer AJ, Klumpp DJ. AOAH remodels arachidonic acid-containing phospholipid pools in a model of interstitial cystitis pain: A MAPP Network study. PLoS One. 2020 Sep 14;15(9):e0235384. doi: 10.1371/journal.pone.0235384. eCollection 2020. [PMID: 32925915] [PMC7489500]
    Keywords: pain; phospholipids; spinal cord; allodynia; transferases; lipids; homeostasis; cell membranes.
  • Clemens JQ, Kutch JJ, Mayer EA, Naliboff BD, Rodriguez LV, Klumpp DJ, Schaeffer AJ, Kreder KJ, Clauw DJ, Harte SE, Schrepf AD, Williams DA, Andriole GL, Lai HH, Buchwald D, Lucia MS, van Bokhoven A, Mackey S, Moldwin RM, Pontari MA, Stephens-Shields AJ, Mullins C, Landis JR. The Multidisciplinary Approach to The Study of Chronic Pelvic Pain (MAPP) Research Network*: Design and implementation of the Symptom Patterns Study (SPS). Neurourol Urodyn. 2020 Aug;39(6):1803-1814. doi: 10.1002/nau.24423. Epub 2020 Jun 23. [PMID: 32578257] [PMC8025696]
    Keywords: chronic; interstitial cystitis; plasma biomarkers; prostatitis; urine biomarkers; urological chronic pelvic pain syndromes.
  • Aguiniga LM, Yang W, Yaggie RE, Schaeffer AJ, Klumpp DJ; MAPP Research Network Study Group. Acyloxyacyl hydrolase modulates depressive-like behaviors through aryl hydrocarbon receptor. Am J Physiol Regul Integr Comp Physiol. 2019 Aug 1;317(2):R289-R300. doi: 10.1152/ajpregu.00029.2019. Epub 2019 Apr 24. [PMID: 31017816] [PMC6732428]
    Keywords: AOAH; AhR; CRF; arachidonic acid; interstitial cystitis; stress.
  • Yang W, Searl TJ, Yaggie R, Schaeffer AJ, Klumpp DJ. A MAPP Network study: overexpression of tumor necrosis factor-? in mouse urothelium mimics interstitial cystitis. Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F36-F44. doi: 10.1152/ajprenal.00075.2017. Epub 2018 Feb 21. [PMID: 29465304] [PMC6087793]
    Keywords: TNF; interstitial cystitis; pelvic pain; transgenic mouse model.
  • Yang W, Yaggie RE, Jiang MC, Rudick CN, Done J, Heckman CJ, Rosen JM, Schaeffer AJ, Klumpp DJ. Acyloxyacyl hydrolase modulates pelvic pain severity. Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1;314(3):R353-R365. doi: 10.1152/ajpregu.00239.2017. Epub 2017 Nov 8. [PMID: 29118019] [PMC5899250]
    Keywords: AOAH; QTL; allodynia; pelvic pain; pseudorabies virus.
  • Kutch JJ, Ichesco E, Hampson JP, Labus JS, Farmer MA, Martucci KT, Ness TJ, Deutsch G, Apkarian AV, Mackey SC, Klumpp DJ, Schaeffer AJ, Rodriguez LV, Kreder KJ, Buchwald D, Andriole GL, Lai HH, Mullins C, Kusek JW, Landis JR, Mayer EA, Clemens JQ, Clauw DJ, Harris RE; MAPP Research Network. Brain signature and functional impact of centralized pain: a multidisciplinary approach to the study of chronic pelvic pain (MAPP) network study. Pain. 2017 Oct;158(10):1979-1991. doi: 10.1097/j.pain.0000000000001001. [PMID: 28692006] [PMC5964335]
    Keywords: Centralized; Chronic; Pain; fMRI; Widespread; Fibromyalgia; Pelvic; VBM; Connectivity.
  • Lai H, Gereau RW 4th, Luo Y, O'Donnell M, Rudick CN, Pontari M, Mullins C, Klumpp DJ. Animal models of urologic chronic pelvic pain syndromes: findings from the multidisciplinary approach to the study of chronic pelvic pain research network. Urology. 2015 Jun;85(6):1454-65. doi: 10.1016/j.urology.2015.03.007. [PMID: 26099889] [PMC4479414]
    Keywords: interstitial cystitis; chronic prostatitis; animal models; pain models; translational research; pelvic pain.
  • Rudick CN, Taylor AK, Yaggie RE, Schaeffer AJ, Klumpp DJ. Asymptomatic bacteriuria Escherichia coli are live biotherapeutics for UTI. PLoS One. 2014 Nov 18;9(11):e109321. doi: 10.1371/journal.pone.0109321. eCollection 2014. [PMID: 25405579] [PMC4236008]
    Keywords: Allodynia; Analgesics; Pain; Bladder; Bacterial pathogens; Urinary tract infections; Antimicrobial resistance; Escherichia coli infections.
  • Landis JR, Williams DA, Lucia MS, Clauw DJ, Naliboff BD, Robinson NA, van Bokhoven A, Sutcliffe S, Schaeffer AJ, Rodriguez LV, Mayer EA, Lai HH, Krieger JN, Kreder KJ, Afari N, Andriole GL, Bradley CS, Griffith JW, Klumpp DJ, Hong BA, Lutgendorf SK, Buchwald D, Yang CC, Mackey S, Pontari MA, Hanno P, Kusek JW, Mullins C, Clemens JQ; MAPP Research Network Study Group. The MAPP research network: design, patient characterization and operations. BMC Urol. 2014 Aug 1;14:58. doi: 10.1186/1471-2490-14-58. [PMID: 25085119] [PMC4126395]
    Keywords: Urologic chronic pelvic pain syndromes; Interstitial cystitis; Chronic prostatitis; Urine biomarkers; Plasma biomarkers; Non-urologic associated syndromes; Quantitative sensory testing (QST); Neuroimaging.
  • Clemens JQ, Mullins C, Kusek JW, Kirkali Z, Mayer EA, Rodríguez LV, Klumpp DJ, Schaeffer AJ, Kreder KJ, Buchwald D, Andriole GL, Lucia MS, Landis JR, Clauw DJ; MAPP Research Network Study Group. The MAPP research network: a novel study of urologic chronic pelvic pain syndromes. BMC Urol. 2014 Aug 1;14:57. doi: 10.1186/1471-2490-14-57. [PMID: 25085007] [PMC4134515]
    Keywords: Urological chronic pelvic pain syndromes; Interstitial cystitis; Chronic prostatitis; Translational research; Multi-disciplinary.
  • Rudick CN, Jiang M, Yaggie RE, Pavlov VI, Done J, Heckman CJ, Whitfield C, Schaeffer AJ, Klumpp DJ. O-antigen modulates infection-induced pain states. PLoS One. 2012;7(8):e41273. doi: 10.1371/journal.pone.0041273. Epub 2012 Aug 10. [PMID: 22899994] [PMC3416823]
    Keywords: Pain; Allodynia; Bladder; Inflammation; Spinal cord; Neutrophils; Bacterial pathogens; Hypersensitivity.