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Publications

• Kilpatrick LA, Gupta A, Tillisch K, Labus JS, Naliboff BD, Mayer EA, Chang L. Neural correlates of perceived and relative resilience in male and female patients with irritable bowel syndrome. Neurogastroenterol Motil. 2024 Feb;36(2):e14710. doi: 10.1111/nmo.14710. Epub 2023 Nov 29. [PMID: 38031358] [PMC11014739]
  Keywords: functional magnetic resonance imaging; irritable bowel syndrome; psychological resilience; sex differences; DK082370 (MAYER, E; RODRIGUEZ L)

• Wang C, Kutch JJ, Labus JS, Yang CC, Harris RE, Mayer EA, Ellingson BM. Reproducible Microstructural Changes in the Brain Associated With the Presence and Severity of Urologic Chronic Pelvic Pain Syndrome (UCPPS): A 3-Year Longitudinal Diffusion Tensor Imaging Study From the MAPP Network. J Pain. 2023 Apr;24(4):627-642. doi: 10.1016/j.jpain.2022.11.008. Epub 2022 Nov 23. [PMID: 36435486] [PMC10676766]
  Keywords: Urological chronic pelvic pain; UCPPS; Longitudinal observation; Diffusion tensor imaging; Probabilistic tractography.

• Jacobs JP, Gupta A, Bhatt RR, Brawer J, Gao K, Tillisch K, Lagishetty V, Firth R, Gudleski GD, Ellingson BM, Labus JS, Naliboff BD, Lackner JM, Mayer EA. Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement. Microbiome. 2021 Nov 30;9(1):236. doi: 10.1186/s40168-021-01188-6. [PMID: 34847963] [PMC8630837]
  Keywords: Cognitive behavioral therapy, Irritable bowel syndrome, Brain-gut-microbiome axis, Neuroimaging, Biomarkers, Outcome prediction; DK082370 (MAYER, E; RODRIGUEZ L)

• Naliboff BD, Schrepf AD, Stephens-Shields AJ, Clemens JQ, Pontari MA, Labus J, Taple BJ, Rodriguez LV, Strachan E, Griffith JW. Temporal relationships between pain, mood and urinary symptoms in urological chronic pelvic pain syndrome: A MAPP Network Study. J Urol. 2021 Jun;205(6):1698-1703. doi: 10.1097/JU.0000000000001595. Epub 2021 Feb 4. [PMID: 33535797] [PMC9179931]
  Keywords: cystitis, interstitial; lower urinary tract symptoms; pain; pelvic pain; prostatitis.
• Sutcliffe S, Gallop R, Henry Lai HH, Andriole GL, Bradley CS, Chelimsky G, Chelimsky T, Quentin Clemens J, Colditz GA, Erickson B, Griffith JW, Kim J, Krieger JN, Labus J, Naliboff BD, Rodriguez LV, Sutherland SE, Taple BJ, Landis JR. A longitudinal analysis of urological chronic pelvic pain syndrome flares in the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. BJU Int. 2019 Sep;124(3):522-531. doi: 10.1111/bju.14783. Epub 2019 May 29. [PMID: 31012513] [PMC6706296]
  Keywords: epidemiology; interstitial cystitis; prostatitis; symptom flare-up.
• Gupta A, Bhatt RR, Naliboff BD, Kutch JJ, Labus JS, Vora PP, Alaverdyan M, Schrepf A, Lutgendorf S, Mayer EA; MAPP Research Network. Impact of early adverse life events and sex on functional brain networks in patients with urological chronic pelvic pain syndrome (UCPPS): A MAPP Research Network study. PLoS One. 2019 Jun 20;14(6):e0217610. doi: 10.1371/journal.pone.0217610. eCollection 2019. [PMID: 31220089] [PMC6586272]
  Keywords: centrality; pain; eigenvectors; neural networks; neuroimaging; caudate nucleus; urology; basal ganglia.
• Woodworth DC, Dagher A, Curatolo A, Sachdev M, Ashe-McNalley C, Naliboff BD, Labus JS, Landis JR, Kutch JJ, Mayer EA, Lee RS, Moses MA, Ellingson BM; MAPP Research Network. Changes in brain white matter structure are associated with urine proteins in urologic chronic pelvic pain syndrome (UCPPS): A MAPP Network study. PLoS One. 2018 Dec 5;13(12):e0206807. doi: 10.1371/journal.pone.0206807. eCollection 2018. [PMID: 30517112] [PMC6281196]
  Keywords: Urinary biomarkers; Diffusion tensor imaging; Brainstem; Pain; Urine; Biomarkers; Brain; Neuroimaging.
• Sutcliffe S, Jemielita T, Lai HH, Andriole GL, Bradley CS, Clemens JQ, Gallop R, Hooton TM, Kreder KJ, Krieger JN, Kusek JW, Labus J, Lucia MS, Mackey S, Naliboff BD, Robinson NA, Rodriguez LV, Stephens-Shields A, van Bokhoven A, Wolin KY, Yan Y, Yang CC, Landis JR, Colditz GA; MAPP Research Network. A case-crossover study of urological chronic pelvic pain syndrome flare triggers in the MAPP Research Network. J Urol. 2018 May;199(5):1245-1251. doi: 10.1016/j.juro.2017.12.050. Epub 2017 Dec 27. [PMID: 29288643] [PMC5911194]
  Keywords: cystitis; interstitial; prostatitis; surveys and questionnaires; symptom flare up; urinary bladder.
• Kutch JJ, Ichesco E, Hampson JP, Labus JS, Farmer MA, Martucci KT, Ness TJ, Deutsch G, Apkarian AV, Mackey SC, Klumpp DJ, Schaeffer AJ, Rodriguez LV, Kreder KJ, Buchwald D, Andriole GL, Lai HH, Mullins C, Kusek JW, Landis JR, Mayer EA, Clemens JQ, Clauw DJ, Harris RE; MAPP Research Network. Brain signature and functional impact of centralized pain: a multidisciplinary approach to the study of chronic pelvic pain (MAPP) network study. Pain. 2017 Oct;158(10):1979-1991. doi: 10.1097/j.pain.0000000000001001. [PMID: 28692006] [PMC5964335]
  Keywords: Centralized; Chronic; Pain; fMRI; Widespread; Fibromyalgia; Pelvic; VBM; Connectivity.
• Kutch JJ, Labus JS, Harris RE, Martucci KT, Farmer MA, Fenske S, Fling C, Ichesco E, Peltier S, Petre B, Guo W, Hou X, Stephens AJ, Mullins C, Clauw DJ, Mackey SC, Apkarian AV, Landis JR, Mayer EA; MAPP Research Network. Resting-state functional connectivity predicts longitudinal pain symptom change in urologic chronic pelvic pain syndrome: a MAPP network study. Pain. 2017 Jun;158(6):1069-1082. doi: 10.1097/j.pain.0000000000000886. [PMID: 28328579] [PMC5435510]
  Keywords: Neuroimaging; Prediction; Chronic pain; Urologic pain.
• Alger JR, Ellingson BM, Ashe-McNalley C, Woodworth DC, Labus JS, Farmer M, Huang L, Apkarian AV, Johnson KA, Mackey SC, Ness TJ, Deutsch G, Harris RE, Clauw DJ, Glover GH, Parrish TB, Hollander Jd, Kusek JW, Mullins C, Mayer EA; MAPP Research Network Investigators. Multisite, multimodal neuroimaging of chronic urological pelvic pain: Methodology of the MAPP Research Network. Neuroimage Clin. 2016 Jan 6;12:65-77. doi: 10.1016/j.nicl.2015.12.009. eCollection 2016. [PMID: 27408791] [PMC4925887]
  Keywords: Brain; Diffusion tensor imaging [DTI]; Functional magnetic resonance imaging; Magnetic resonance imaging; TransMAPP; Urologic chronic pelvic pain syndromes.
• Woodworth D, Mayer E, Leu K, Ashe-McNalley C, Naliboff BD, Labus JS, Tillisch K, Kutch JJ, Farmer MA, Apkarian AV, Johnson KA, Mackey SC, Ness TJ, Landis JR, Deutsch G, Harris RE, Clauw DJ, Mullins C, Ellingson BM; MAPP Research Network. Unique microstructural changes in the brain associated with urological chronic pelvic pain syndrome (UCPPS) revealed by diffusion tensor MRI, super-resolution track density imaging, and statistical parameter mapping: A MAPP Network Neuroimaging Study. PLoS One. 2015 Oct 13;10(10):e0140250. doi: 10.1371/journal.pone.0140250. eCollection 2015. [PMID: 26460744] [PMC4604194]
  Keywords: Pain; Central nervous system; Corpus callosum; Diffusion tensor imaging; Basal ganglia; Microstructure; Anisotropy; Pain sensation.
• Martucci KT, Shirer WR, Bagarinao E, Johnson KA, Farmer MA, Labus JS, Apkarian AV, Deutsch G, Harris RE, Mayer EA, Clauw DJ, Greicius MD, Mackey SC. The posterior medial cortex in urologic chronic pelvic pain syndrome: detachment from default mode network-a resting-state study from the MAPP Research Network. Pain. 2015 Sep;156(9):1755-1764. doi: 10.1097/j.pain.0000000000000238. [PMID: 26010458] [PMC4545714]
  Keywords: UCPPS; Interstitial cystitis; Bladder pain syndrome; Posterior cingulate cortex; Default mode network [DMN]; Precuneus; Dual regression; Resting state; fMRI.
• Kutch JJ, Yani MS, Asavasopon S, Kirages DJ, Rana M, Cosand L, Labus JS, Kilpatrick LA, Ashe-McNalley C, Farmer MA, Johnson KA, Ness TJ, Deutsch G, Harris RE, Apkarian AV, Clauw DJ, Mackey SC, Mullins C, Mayer EA. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study. Neuroimage Clin. 2015 Jun 5;8:493-502. doi: 10.1016/j.nicl.2015.05.013. eCollection 2015. [PMID: 26106574] [PMC4474411]
  Keywords: brain mapping; Brief Pain Inventory; chronic prostatitis; functional magnetic resonance imaging; Functional Neuroimaging; image processing; magnetic resonance imaging; motoneuron; motor control; motor cortex; muscle contraction; nerve cell network; Nerve Net; neuroimaging; nuclear magnetic resonance imaging; pathophysiology; pelvis pain syndrome; posterior insula; prostatitis; resting state network.
• Bagarinao E, Johnson KA, Martucci KT, Ichesco E, Farmer MA, Labus J, Ness TJ, Harris R, Deutsch G, Apkarian VA, Mayer EA, Clauw DJ, Mackey S. Preliminary structural MRI based brain classification of chronic pelvic pain: A MAPP network study. Pain. 2014 Dec;155(12):2502-2509. doi: 10.1016/j.pain.2014.09.002. Epub 2014 Sep 19. [PMID: 25242566] [PMC4504202]
  Keywords: Gray matter density; Machine learning; SVM; Support vector machine; UCPPS.
• Kilpatrick LA, Kutch JJ, Tillisch K, Naliboff BD, Labus JS, Jiang Z, Farmer MA, Apkarian AV, Mackey S, Martucci KT, Clauw DJ, Harris RE, Deutsch G, Ness TJ, Yang CC, Maravilla K, Mullins C, Mayer EA. Alterations in resting state oscillations and connectivity in sensory and motor networks in women with interstitial cystitis/painful bladder syndrome. J Urol. 2014 Sep;192(3):947-55. doi: 10.1016/j.juro.2014.03.093. Epub 2014 Mar 26. [PMID: 24681331] [PMC4432915]
  Keywords: brain mapping; cystitis; interstitial; magnetic resonance imaging; pain; urinary bladder.