People

Publications

• Schrepf A, Kaplan C, Harris RE, Williams DA, Clauw DJ, As-Sanie S, Till S, Clemens JQ, Rodriguez LV, Van Bokhoven A, Landis R, Gallop R, Bradley C, Naliboff B, Pontari M, O'Donnell M, Luo Y, Kreder K, Lutgendorf SK, Harte SE. Stimulated whole-blood cytokine/chemokine responses are associated with interstitial cystitis/bladder pain syndrome phenotypes and features of nociplastic pain: a multidisciplinary approach to the study of chronic pelvic pain research network study. Pain. 2023 May 1;164(5):1148-1157. doi: 10.1097/j.pain.0000000000002813. [PMID: 36279178] [PMC10106356]
  Keywords: Chronic pain; Interstitial cystitis/bladder pain syndrome; toll-like receptor.
• Farrar JT, Locke KT Jr., Clemens JQ, Griffith JW, Harte SE, Kirkali Z, Kreder KJ, Krieger JN, Lai HH, Moldwin RM, Mullins C, Naliboff BD, Pontari MA, Rodriguez LV, Schaeffer AJ, Schrepf A, Stephens-Shields A, Sutcliffe S, Taple BJ, Williams DA, Landis JR. Widespread Pain Phenotypes Impact Treatment Efficacy Results in Randomized Clinical Trials for Interstitial Cystitis/Bladder Pain Syndrome: A MAPP Network Study. Res Sq. 2023 Feb 23;rs.3.rs-2441086. doi: 10.21203/rs.3.rs-2441086/v1. Preprint [PMID: 36865104] [PMC9980200]
  Keywords: Randomized controlled trials; Chronic pain; Epidemiology; Functional clustering.
• Schrepf A, Gallop R, Naliboff B, Harte SE, Afari N, Lai HH, Pontari M, McKernan LC, Strachan E, Kreder KJ, As-Sanie SA, Rodriguez LV, Griffith JW, Williams DA; Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. Clinical Phenotyping for Pain Mechanisms in Urologic Chronic Pelvic Pain Syndromes: A Mapp Research Network Study. J Pain. 2022 Sep;23(9):1594-1603. doi: 10.1016/j.jpain.2022.03.240. Epub 2022 Apr 25. [PMID: 35472518] [PMC10547025]
  Keywords: Nociceptive pain; central nervous system sensitization; chronic pain; cystitis; neuropathic pain.
• Naliboff BD, Locke K Jr, Schrepf D, Griffith JW, Moldwin R, Krieger JN, Rodriguez LV, Stephens-Shields AJ, Clemens JQ, Lai HH, Sutcliffe S, Taple BJ, Williams D, Pontari MA, Mullins C, Landis JR; MAPP Research Network. Reliability and validity of pain and urinary symptom severity assessment in urologic chronic pelvic pain; A MAPP Network Analysis. J Urol. 2022 Jun;207(6):1246-1255. doi: 10.1097/JU.0000000000002438. Epub 2022 Jan 21. [PMID: 35060778] [PMC10494963]
  Keywords: cystitis, interstitial; lower urinary tract symptoms; pelvic pain; prostatitis.
• Guo, WS; You, MY; Yi, JL; Pontari, MA; Landis, JR. Functional Mixed Effects Clustering with Application to Longitudinal Urologic Chronic Pelvic Pain Syndrome Symptom Data. J Am Stat Assoc. 2022;117(540):1631-1641. doi: 10.1080/01621459.2022.2066536. Epub 2022 May 13. [PMID: 36845296] [PMC9949755]
  Keywords: Functional clustering; Kullback-Leibler information criterion; Smoothing Spline; State Space model.
• Naliboff BD, Schrepf AD, Stephens-Shields AJ, Clemens JQ, Pontari MA, Labus J, Taple BJ, Rodriguez LV, Strachan E, Griffith JW. Temporal relationships between pain, mood and urinary symptoms in urological chronic pelvic pain syndrome: A MAPP Network Study. J Urol. 2021 Jun;205(6):1698-1703. doi: 10.1097/JU.0000000000001595. Epub 2021 Feb 4. [PMID: 33535797] [PMC9179931]
  Keywords: cystitis, interstitial; lower urinary tract symptoms; pain; pelvic pain; prostatitis.

• Roy R, Stephens AJ, Daisy C, Merritt L, Newcomb CW, Yang J, Dagher A, Curatolo A, Sachdev M, McNeish B, Landis R, van Bokhoven A, El-Hayek A, Froehlich J, Pontari MA, Zurakowski D, Lee RS, Moses MA. Association of longitudinal changes in symptoms and urinary biomarkers in patients with urological chronic pelvic pain syndrome: A MAPP Research Network Study. J Urol. 2021 Feb;205(2):514-523. doi: 10.1097/JU.0000000000001391. Epub 2020 Oct 7. [PMID: 33026902] [PMC8139408]
  Keywords: lipocalin-2; matrix metalloproteinases; pelvic pain; vascular endothelial growth factor; vascular endothelial growth factor receptor.

• Clemens JQ, Kutch JJ, Mayer EA, Naliboff BD, Rodriguez LV, Klumpp DJ, Schaeffer AJ, Kreder KJ, Clauw DJ, Harte SE, Schrepf AD, Williams DA, Andriole GL, Lai HH, Buchwald D, Lucia MS, van Bokhoven A, Mackey S, Moldwin RM, Pontari MA, Stephens-Shields AJ, Mullins C, Landis JR. The Multidisciplinary Approach to The Study of Chronic Pelvic Pain (MAPP) Research Network*: Design and implementation of the Symptom Patterns Study (SPS). Neurourol Urodyn. 2020 Aug;39(6):1803-1814. doi: 10.1002/nau.24423. Epub 2020 Jun 23. [PMID: 32578257] [PMC8025696]
  Keywords: chronic; interstitial cystitis; plasma biomarkers; prostatitis; urine biomarkers; urological chronic pelvic pain syndromes.
• Clemens JQ, Mullins C, Ackerman AL, Bavendam T, van Bokhoven A, Ellingson BM, Harte SE, Kutch JJ, Lai HH, Martucci KT, Moldwin R, Naliboff BD, Pontari MA, Sutcliffe S, Landis JR; MAPP Research Network Study Group. Urologic chronic pelvic pain syndrome: insights from the MAPP Research Network. Nat Rev Urol. 2019 Mar;16(3):187-200. doi: 10.1038/s41585-018-0135-5. [PMID: 30560936] [PMC6800057]
  Keywords: bladder/bladder disease; Urologic chronic pelvic pain syndromes; chronic pain; prostatitis.
• Schrepf A, Williams DA, Gallop R, Naliboff BD, Basu N, Kaplan C, Harper DE, Landis JR, Clemens JQ, Strachan E, Griffith JW, Afari N, Hassett A, Pontari MA, Clauw DJ, Harte SE; MAPP Research Network. Sensory sensitivity and symptom severity represent unique dimensions of chronic pain: a MAPP Research Network study. Pain. 2018 Oct;159(10):2002-2011. doi: 10.1097/j.pain.0000000000001299. [PMID: 29863527] [PMC6705610]
  Keywords: Interstitial cystitis/painful bladder syndrome; Factor analysis; statistical; Fibromyalgia; Central nervous system sensitization; Interoception.
• Dagher A, Curatolo A, Sachdev M, Stephens AJ, Mullins C, Landis JR, van Bokhoven A, El-Hayek A, Froehlich JW, Briscoe AC, Roy R, Yang J, Pontari MA, Zurakowski D, Lee RS, Moses MA; MAPP Research Network. Identification of novel non-invasive biomarkers of urinary chronic pelvic pain syndrome: findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. BJU Int. 2017 Jul;120(1):130-142. doi: 10.1111/bju.13832. Epub 2017 Apr 11. [PMID: 28263447] [PMC5951631]
  Keywords: Lipocalin 2 (also known as NGAL); Multidisciplinary Approach to the Study of Chronic Pelvic Pain; matrix metalloproteinase; neutrophil gelatinase associated lipocalin; vascular endothelial growth factor; vascular endothelial growth factor receptor 1.
• Griffith JW, Stephens-Shields AJ, Hou X, Naliboff BD, Pontari M, Edwards TC, Williams DA, Clemens JQ, Afari N, Tu F, Lloyd RB, Patrick DL, Mullins C, Kusek JW, Sutcliffe S, Hong BA, Lai HH, Krieger JN, Bradley CS, Kim J, Landis JR. Pain and urinary symptoms should not be combined into a single score: psychometric findings from the MAPP Research Network. J Urol. 2016 Apr;195(4 Pt 1):949-54. doi: 10.1016/j.juro.2015.11.012. Epub 2015 Nov 14. [PMID: 26585679] [PMC4867140]
  Keywords: chronic pain; cystitis, interstitial; factor analysis, statistical; prostatitis; urinary bladder.
• Lai HH, Krieger JN, Pontari MA, Buchwald D, Hou X, Landis JR; MAPP Research Network. Painful bladder filling and painful urgency are distinct characteristics in men and women with urological chronic pelvic pain syndromes: A MAPP Research Network Study. J Urol. 2015 Dec;194(6):1634-41. doi: 10.1016/j.juro.2015.05.105. Epub 2015 Jul 17. [PMID: 26192257] [PMC4669971]
  Keywords: cystitis; interstitial; pain; prostatitis; questionnaires; urinary bladder.
• Lai H, Gereau RW 4th, Luo Y, O'Donnell M, Rudick CN, Pontari M, Mullins C, Klumpp DJ. Animal models of urologic chronic pelvic pain syndromes: findings from the multidisciplinary approach to the study of chronic pelvic pain research network. Urology. 2015 Jun;85(6):1454-65. doi: 10.1016/j.urology.2015.03.007. [PMID: 26099889] [PMC4479414]
  Keywords: interstitial cystitis; chronic prostatitis; animal models; pain models; translational research; pelvic pain.
• Landis JR, Williams DA, Lucia MS, Clauw DJ, Naliboff BD, Robinson NA, van Bokhoven A, Sutcliffe S, Schaeffer AJ, Rodriguez LV, Mayer EA, Lai HH, Krieger JN, Kreder KJ, Afari N, Andriole GL, Bradley CS, Griffith JW, Klumpp DJ, Hong BA, Lutgendorf SK, Buchwald D, Yang CC, Mackey S, Pontari MA, Hanno P, Kusek JW, Mullins C, Clemens JQ; MAPP Research Network Study Group. The MAPP research network: design, patient characterization and operations. BMC Urol. 2014 Aug 1;14:58. doi: 10.1186/1471-2490-14-58. [PMID: 25085119] [PMC4126395]
  Keywords: Urologic chronic pelvic pain syndromes; Interstitial cystitis; Chronic prostatitis; Urine biomarkers; Plasma biomarkers; Non-urologic associated syndromes; Quantitative sensory testing (QST); Neuroimaging.