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Activation of spinal extracellular signal-regulated kinases (ERK) 1/2 is associated with the development of visceral hyperalgesia of the bladder.

Lai HH, Qiu CS, Crock LW, Morales MEP, Ness TJ, Gereau RW 4th. Activation of spinal extracellular signal-regulated kinases (ERK) 1/2 is associated with the development of visceral hyperalgesia of the bladder. Pain. 2011 Sep;152(9):2117-2124. doi: 10.1016/j.pain.2011.05.017. Epub 2011 Jun 25. [PMID: 21705143] [PMC3157542]
Keywords: Urinary bladder; Visceral pain; Inflammatory pain; Visceromotor response; ERK signaling; Central sensitization.

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